Document Type : Original Article
Authors
1
Medicinal Chemistry Department, Theodor Bilharz Research Institute, Kornaish El Nile, Warrak El-Hadar, Imbaba (P.O. 30), Giza, 12411, Egypt
2
Chemistry of Natural Product Department, Ministry of Education, Anbar Education Directorate, Iraq
3
Environmental Research Department, Theodor Bilharz Research Institute (TBRI), P.O. Box 30 -12411, Giza, Egypt.
4
Environmental Research Department, Theodor Bilharz Research Institute
Abstract
In recent years, wastewater treatment technologies have garnered more attention as the world pursues fulfilling the Sustainable Development Goals (SDGs). This study has pointed to the role of wastewater control that plays toward achieving one of the SDGs: clean water and sanitation. In this work, the phytochemical screening of Calotropis procera leaf extract detected the appearance of various classes of secondary metabolites involving saponins, phenols, flavonoids, anthocyanins, terpenoids, and tannins. Moreover, HPLC examination revealed that the investigated extract comprises phenolic acids and flavonoids. The average size of semi-spherical zinc oxide nanoparticles is 30.27nm; they were fabricated and conjugated with C. procera leaf extract to improve the antimicrobial activity. The results in this study recorded significant antimicrobial performance of ZnO NPs and C. procera leaf extract; however, the synthesized CP@ZnO nanocomposite showed maximum antimicrobial activities against the most strains found in wastewater in a relatively low concentration (MIC= 50, 75, and 35µg/ l for S. aureus, E. coli, and C. albicans, respectively). The novel CP@ZnO nanocomposite is considered to be an efficient and safe antimicrobial agent and effective for wastewater treatment in local communities to provide unconventional water sources from water reuse.
Keywords
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