Zaghloul et al., K. (2023). Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish. Egyptian Journal of Aquatic Biology and Fisheries, 27(4), 825-845. doi: 10.21608/ejabf.2023.313124
Khalid H. Zaghloul et al.. "Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish". Egyptian Journal of Aquatic Biology and Fisheries, 27, 4, 2023, 825-845. doi: 10.21608/ejabf.2023.313124
Zaghloul et al., K. (2023). 'Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish', Egyptian Journal of Aquatic Biology and Fisheries, 27(4), pp. 825-845. doi: 10.21608/ejabf.2023.313124
Zaghloul et al., K. Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish. Egyptian Journal of Aquatic Biology and Fisheries, 2023; 27(4): 825-845. doi: 10.21608/ejabf.2023.313124
Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish
A total of seventy-two healthy Nile catfish; Clarias gariepinus were distributed into four distinct groups. These groups were fed either a commercial basal diet or a diet enriched with 500 mg curcumin/kg ration for 12 weeks. Among these groups, two groups were exposed to a sublethal concentration of copper (0.35 mg/l) and were fed a normal diet or a curcumin-enriched diet as an antioxidant. The other two control groups were comprised of fish raised in dechlorinated tap water and were fed either the commercial basal diet or the curcumin-supplemented diet for the same 12-week experimental period. The study’s findings revealed that Clarias gariepinus, when subjected to a sublethal copper concentration (0.35 mg/l), accumulated a greater amount of copper in their vital organs (gills, liver, and muscles) after 12 weeks. This accumulation coincided with a decrease in fish’s rate of growth and quality of meat (indicated by higher muscle water content and ash but lower muscle total protein and lipids), a reduction in RBCs count, Hb content, and Ht values, and an increase in WBCs count, serum glucose, creatinine, uric acid, total protein, albumin, globulin levels, A/G ratio, and AST, ALT and ALP activities when compared to the control group of fish with a highly significant difference (P < 0.01). However, fish that were exposed to copper toxicity and fed curcumin supplemented diet (500 mg/kg diet) exhibited values that were more or less similar to those of the control group of fish that were reared in dechlorinated tap water and fed a commercial basal diet or curcumin supplemented basal diet (500mg/kg diet).
View on SCiNiTO
Top