Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction

Document Type : Original Article

Authors

Abstract

The present study was performed to establish the toxicological impact of barium chloride (BaCl2) on freshwater fish Cirrhinus mrigala. In this direction we have investigated the ecological impact of BaCl2 on C mrigala, a freshwater fish widely consumed. Biochemical, neurochemical, and physiological variations were carried out in the present study, and LC50 of BaCl2 was found to be 12 ppm, observed for 24hrs. Further 1/10th of the LC50 concentration of BaCl2 (1.2 ppm) was selected for acute investigation for 96hrs. The results exhibited an increase in serum lactate dehydrogenase (LDH), aspartate transaminase (AST), and alanine transaminase (ALT) levels compared to control groups. Studies revealed alterations in oxidative stress markers with a notable lowering in the serum superoxide dismutase (SOD), and catalase (CAT) levels, and an increase in malondialdehyde (MDA). The studies reported an elevation in brain glutamate concentrations indicating brain tissue damage. The study highlights the potential toxicological impact of BaCl2 on freshwater fish.

Files

Share

How to cite

Statistics