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Chandra S., J., Mahadimane P., V., Saqib, A., Sukumaran, S., Chandra SP, S. (2020). Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction. Egyptian Journal of Aquatic Biology and Fisheries, 24(7- Special issue), 995-1003. doi: 10.21608/ejabf.2020.144745
Jagadeep Chandra S.; Vishwaprakash Mahadimane P.; Asma Saqib; Sandya Sukumaran; Sharath Chandra SP. "Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction". Egyptian Journal of Aquatic Biology and Fisheries, 24, 7- Special issue, 2020, 995-1003. doi: 10.21608/ejabf.2020.144745
Chandra S., J., Mahadimane P., V., Saqib, A., Sukumaran, S., Chandra SP, S. (2020). 'Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction', Egyptian Journal of Aquatic Biology and Fisheries, 24(7- Special issue), pp. 995-1003. doi: 10.21608/ejabf.2020.144745
Chandra S., J., Mahadimane P., V., Saqib, A., Sukumaran, S., Chandra SP, S. Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction. Egyptian Journal of Aquatic Biology and Fisheries, 2020; 24(7- Special issue): 995-1003. doi: 10.21608/ejabf.2020.144745

Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction

Article 58, Volume 24, 7- Special issue, November and December 2020, Page 995-1003  XML PDF (340.97 K)
Document Type: Original Article
DOI: 10.21608/ejabf.2020.144745
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Authors
Jagadeep Chandra S.; Vishwaprakash Mahadimane P.; Asma Saqib; Sandya Sukumaran; Sharath Chandra SP
Abstract
The present study was performed to establish the toxicological impact of barium chloride (BaCl2) on freshwater fish Cirrhinus mrigala. In this direction we have investigated the ecological impact of BaCl2 on C mrigala, a freshwater fish widely consumed. Biochemical, neurochemical, and physiological variations were carried out in the present study, and LC50 of BaCl2 was found to be 12 ppm, observed for 24hrs. Further 1/10th of the LC50 concentration of BaCl2 (1.2 ppm) was selected for acute investigation for 96hrs. The results exhibited an increase in serum lactate dehydrogenase (LDH), aspartate transaminase (AST), and alanine transaminase (ALT) levels compared to control groups. Studies revealed alterations in oxidative stress markers with a notable lowering in the serum superoxide dismutase (SOD), and catalase (CAT) levels, and an increase in malondialdehyde (MDA). The studies reported an elevation in brain glutamate concentrations indicating brain tissue damage. The study highlights the potential toxicological impact of BaCl2 on freshwater fish.
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